Ufasomes-based drug delivery from Creative Biolabs's blog

Scientists at Creative Biolabs are expert in targeted delivery system research. We have a series of innovative and advanced platforms to provide fast and convenient liposome development services for our worldwide customers. Currently, we can provide affordable, high-quality Ufasomes-based drug delivery services for diseases diagnosis and therapeutic with unbeatable rapid turnaround times.

Ufasomes (unsaturated fatty acid vesicles) are suspensions of closed lipid bilayers that consist of fatty acids, and their ionized species (soap) which are restricted to narrow pH range from 7 to 9. In ufasomes, fatty acid molecules are targeted where their hydrocarbon tails are directed toward the membrane interior and the carboxyl groups are in contact with water. The formation of ufasomes is considered to result from associative interaction in mixtures of fully ionized and unionized fatty acids at pH > 7.0. Stability of ufasomes relies on suitable selection of fatty acid, amount of cholesterol, buffer, pH range, amount of lipoxygenase, and the presence of divalent cations. Recent innovative improvement renders advancement to formulate ufasomes with tailorable features such as extension of pH range, insensitivity toward divalent cations, and enhanced stability.