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OPANA ER (oxymorphone hydrochloride extended-release)is a prescription pain medication used to manage moderate to severe pain that is expected to last for an extended period of time. It is an opioid pain medication, which means it works by changing the way the brain and nervous system perceive pain. It is important to use this medication only as directed and to never take more than prescribed.
How does it work?
OPANA ER works by binding to specific receptors in the brain and nervous system, called opioid receptors. This binding changes the way that pain signals are perceived and reduces the sensation of pain. The extended-release formulation of OPANA ER is designed to provide pain relief for an extended period of time, reducing the need for multiple doses throughout the day.
However, it is important to note that the use of opioids like OPANA ER can also lead to physical dependence and tolerance, meaning that over time the body may adjust to the presence of the drug and require more to achieve the same pain-relieving effects. Additionally, there is a risk for abuse, overdose, and addiction with the use of opioid medications. Therefore, it is important to only use OPANA ER as directed by a healthcare provider and to never take more than prescribed.
How to take it?
OPANA ER is taken orally, usually once every 12 hours, with or without food. The recommended starting dose of OPANA ER varies depending on the patient's individual pain management needs, as well as other factors such as their age, medical history, and current medication regimen.
It is important to follow the dosing instructions provided by your healthcare provider and to never take more than the prescribed amount. Taking too much OPANA ER can result in serious adverse effects, including overdose and death. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.
Additionally, it is important to never crush, break, or dissolve the extended-release tablets, as this can cause a sudden release of the entire dose, which can lead to overdose and death. Always swallow the tablets whole. If you have trouble swallowing the tablets, you can mix the crushed tablets with a small amount of water, but be sure to swallow the mixture immediately without chewing.
Remember, OPANA ER is a prescription medication that should only be used as directed by a healthcare provider and never shared with others, as doing so is illegal and can be dangerous.
DosagesThe recommended starting dose of OPANA ER varies depending on the individual needs of the patient and other factors, such as their age, medical history, and current medication regimen.
The usual starting dose for adults with moderate to severe pain is 10 mgto 20 mgevery 12 hours. The dose may be increased by your healthcare provider as needed, but should not exceed 80 mg in a 24-hour period.
Elderly patients and patients with hepatic impairment may require a lower starting dose, as their metabolism of the drug may be slower. Your healthcare provider will determine the most appropriate starting dose for you based on your specific needs and medical history.
It is important to never take more than the prescribed dose of OPANA ER, as doing so can result in serious adverse effects, including overdose and death. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.
It is also important to never crush, break, or dissolve the extended-release tablets, as this can cause a sudden release of the entire dose, which can lead to overdose and death. Always swallow the tablets whole. If you have trouble swallowing the tablets, you can mix the crushed tablets with a small amount of water, but be sure to swallow the mixture immediately without chewing.
Remember, the dose of OPANA ER that is appropriate for you is determined by your healthcare provider and should never be adjusted without their approval. If you have any questions or concerns about your dose, it is important to discuss these with your healthcare provider.
Side Effects
OPANA ER, like all medications, can cause side effects. Some common side effects of OPANA ER include:
Nausea
Vomiting
Constipation
Dizziness
Drowsiness
Headache
Sweating
Dry mouth
Itching
In some cases, these side effects may be temporary and go away on their own as your body adjusts to the medication. However, if they persist or become severe, it is important to contact your healthcare provider.
More serious side effects of OPANA ER can occur, including:
Slow or shallow breathing
Confusion
Seizures
Fainting
Low blood pressure
Hives
Swelling of the face, lips, tongue, or throat
If you experience any of these serious side effects, seek medical attention immediately.
It is also important to be aware of the risk of opioid-related adverse effects, including addiction, overdose, and death. If you suspect that you or someone else has taken an overdose of OPANA ER, seek emergency medical attention immediately.
If you have any concerns about the side effects of OPANA ER, or if you experience any unexpected symptoms, it is important to contact your healthcare provider.
Precaution
There are several precautions to be aware of when taking OPANA ER, including:
Only use as directed: OPANA ER should only be taken as directed by your healthcare provider and never taken in larger amounts or for a longer period of time than prescribed.
Risk of addiction: OPANA ER is a strong opioid medication and has a high potential for abuse, addiction, and overdose. If you have a history of substance abuse, it is important to discuss this with your healthcare provider.
Avoid alcohol: Alcohol can increase the sedative effects of OPANA ER and should be avoided while taking this medication.
Avoid driving or operating heavy machinery: OPANA ER can cause drowsiness, dizziness, and impaired judgment, making it unsafe to drive or operate heavy machinery. Wait until you know how the medication affects you before engaging in these activities.
Interactions with other medications: OPANA ER can interact with other medications, including other pain medications, sedatives, muscle relaxants, and antidepressants. Be sure to tell your healthcare provider about all the medications you are taking, including prescription and over-the-counter drugs, as well as supplements and herbal products.
Pregnancy and breastfeeding: OPANA ER should not be used during pregnancy, as it can cause harm to the developing fetus. Women who are breastfeeding should also avoid using this medication, as it can pass into breast milk and cause harm to a nursing infant.
Withdrawal symptoms: If you have been taking OPANA ER for an extended period of time and suddenly stop taking it, you may experience withdrawal symptoms, including anxiety, agitation, irritability, muscle aches, sweating, and chills. It is important to talk to your healthcare provider before stopping or reducing the dose of this medication.
Pre-existing conditions: If you have a history of liver or kidney disease, lung or breathing problems, head injury, seizures, or mental health problems, it is important to discuss these conditions with your healthcare provider before taking OPANA ER.
It is important to follow all of the precautions and guidelines provided by your healthcare provider when taking OPANA ER, in order to minimize the risk of adverse effects and ensure safe and effective use of this medication.
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