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DNA modifying enzymes play a key role in the development of various medical and industrial applications. An important tool for analyzing the activity and specificity of these enzymes is clustering analysis. Cluster analysis is a bioinformatics technique involving the grouping of related sequences based on similarity. Cluster analysis allows researchers to group similar enzyme sequences and identify conserved patterns that are critical to enzyme function. This information can be used to develop more efficient enzymes or improve existi... more

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Contact maps published in Nature Biotechnology reveal direct contacts or protein interactions between more than 200 proteins. The International Union of Scientists, led by Dr. Pascal Falter-Braun, Director of the Helmholtz Institute for Network Biology (INET) in Munich at the University of Ludwig-Maximilan (LMU) in Munich and Professor of the School of Biology, includes teams from Canada, the United States, France, Spain, and Belgium. Scientists at the Laboratory of Structural Bioinformatics and Network Biology, led by Dr. ... more